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Competitive inhibition of side chain oxidation of 3 alpha, 7 alpha-dihydroxy-5 beta-cholestan-26-oic acid by 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestan-26-oic acid in the hamster.

3 alpha,7 alpha-dihydroxy-5 beta-cholestan-26-oic acid (DHCA) and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestan-26-oic acid (THCA) are metabolized into chenodeoxycholic acid and cholic acid, respectively, through oxidation and cleavage of the terminal three carbons of the side chain. The pres...

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Autori principali: O W Cass, G C Williams, R F Hanson
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 1980-02-01
Serie:Journal of Lipid Research
Accesso online:http://www.sciencedirect.com/science/article/pii/S0022227520398242
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