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Chitosan fortified repaglinide gastro-retentive mucoadhesive microsphere with improved anti-diabetic attribute

Repaglinide (RPG) has a high rate of absorption from the gastrointestinal system after oral administration due to low log P value. Hence, in this study the inotropic gelation process was used to fabricate mucoadhesive microspheres of RPG using biodegradable polymers such as guar gum, chitosan, and f...

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Principais autores: Anil Pawar, Pranjal Lohakane, Ramdas Pandhare, Popat Mohite, Shubham Munde, Sudarshan Singh, Vijay Chidrawar
Format: Artigo
Sprog:Inglês
Udgivet: KeAi Communications Co., Ltd. 2024-06-01
Serier:Intelligent Pharmacy
Fag:
Biodegradable polymers
Chitosan
Guar gum
Fenugreek
Microspheres
Repaglinide
Online adgang:http://www.sciencedirect.com/science/article/pii/S2949866X24000224
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