Cell Differentiation Trajectory in Liver Cirrhosis Predicts Hepatocellular Carcinoma Prognosis and Reveals Potential Biomarkers for Progression of Liver Cirrhosis to Hepatocellular Carcinoma

Most hepatocellular carcinoma (HCC) patients occur on a background of liver cirrhosis, the molecular mechanisms of liver cirrhosis and its progression to HCC remain to be fully elucidated. Single cell differentiation trajectory analysis has been used in cell classification and tumor molecular typing...

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Hlavní autoři:	Zhaobin He, Cheng Peng, Tianen Li, Jie Li
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-03-01
Edice:	Frontiers in Genetics
Témata:	differentiation trajectory scRNA-seq liver cirrhosis hepatocellular carcinoma molecular typing
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fgene.2022.858905/full
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