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LyeTx I-b Peptide Attenuates Tumor Burden and Metastasis in a Mouse 4T1 Breast Cancer Model

Cationic anticancer peptides have exhibited potent anti-proliferative and anti-inflammatory effects in neoplastic illness conditions. LyeTx I-b is a synthetic peptide derived from <i>Lycosa erythrognatha</i> spider venom that previously showed antibiotic activity in vitro and in vivo. This study foc...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Mostafa A. L. Abdel-Salam, Bárbara Pinto, Geovanni Cassali, Lilian Bueno, Gabriela Pêgas, Fabrício Oliveira, Irismara Silva, André Klein, Elaine Maria de Souza-Fagundes, Maria Elena de Lima, Juliana Carvalho-Tavares
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-09-01
Schriftenreihe:Antibiotics
Schlagworte:
breast cancer
LyeTx I-b peptide
immunomodulation
leukocyte recruitment
cytokines
anticancer activity of LyeTx I-b
Online-Zugang:https://www.mdpi.com/2079-6382/10/9/1136
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