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Combined elevation of myeloid-derived suppressor cells and Tregs predicts lymph node metastasis in breast cancer

Abstract Background This study investigates the clinical significance of myeloid-derived suppressor cells (MDSCs), including polymorphonuclear MDSCs (PMN-MDSCs) and monocytic MDSCs (M-MDSCs) subsets, and regulatory T cells (Tregs) in the peripheral blood of breast cancer patients. Methods Using flow...

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Principais autores: Huichao Zhang, Xiaojie Yin, Sifan Wang, Qingjing Li, Longfei Xia, Jingfu Qiu, Wei Li, Hong Li, Feng Zhao, Yuan Song
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-11-01
Serier:BMC Cancer
Fag:
Breast cancer
MDSCs
PMN-MDSCs
M-MDSCs
Tregs
ROC curve analysis
Online adgang:https://doi.org/10.1186/s12885-025-15277-4
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