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Pluronic L81 enhances triacylglycerol accumulation in the cytosol and inhibits chylomicron secretion

Pluronic L81 (PL81) inhibits fat absorption, and other Pluronic copolymers help overcome drug resistance in cancer cells. To understand how PL81 acts, we synthesized a radiolabeled analog, [14C]PL81, and showed that it was structurally similar to PL81 based on 1H NMR as well as mass spectrometric an...

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Hlavní autoři: Sumbul Fatma, Reuven Yakubov, Kamran Anwar, M. Mahmood Hussain
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2006-11-01
Edice:Journal of Lipid Research
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S0022227520433784
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