Biophysical fitness landscapes for transcription factor binding sites.
Phenotypic states and evolutionary trajectories available to cell populations are ultimately dictated by complex interactions among DNA, RNA, proteins, and other molecular species. Here we study how evolution of gene regulation in a single-cell eukaryote S. cerevisiae is affected by interactions bet...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2014-07-01
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| Serier: | PLoS Computational Biology |
| Online adgang: | http://europepmc.org/articles/PMC4091707?pdf=render |
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