Clinical implication of thiopurine methyltransferase polymorphism in children with acute lymphoblastic leukemia: A preliminary Egyptian study

Background: 6-mercaptopurine (6-MP) is an essential component of pediatric acute lymphoblastic leukemia (ALL) maintenance therapy. Individual variability in this drug-related toxicity could be attributed in part to genetic polymorphism thiopurine methyltransferase (TPMT). Aim: To investigate the fre...

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Autores principales:	Farida H El-Rashedy, Seham Mohammed Ragab, Ashraf A Dawood, Shaymaa A Temraz
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2015-01-01
Colección:	Indian Journal of Medical and Paediatric Oncology
Materias:	6-mercaptopurine acute lymphoblastic leukemia pharmacogenetic polymorphism thiopurine methyltransferase
Acceso en línea:	http://www.ijmpo.org/article.asp?issn=0971-5851;year=2015;volume=36;issue=4;spage=265;epage=270;aulast=El-Rashedy
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