Down-Regulation of Collagen Hydroxylation in Colorectal Liver Metastasis

Collagen is significantly upregulated in colorectal liver metastasis (CRLM) compared to liver tissue. Expression levels of specific collagen types in CRLM resemble those in colorectal cancer (CRC) and colon tissue. We investigated whether the collagen hydroxylation pattern from the primary tumor als...

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Autores principales:	Nick A. van Huizen, Peter C. Burgers, Joost van Rosmalen, Michail Doukas, Jan N. M. IJzermans, Theo M. Luider
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2020-09-01
Colección:	Frontiers in Oncology
Materias:	post-translational modification mass spectrometry colorectal cancer colorectal liver metastasis collagen hydroxyproline
Acceso en línea:	https://www.frontiersin.org/article/10.3389/fonc.2020.557737/full
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