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Transcriptomic profiling of lung alveolar macrophages reveals distinct contribution of sterol metabolism in macrophage response to Cryptococcus gattii infection.

Alveolar macrophages are well known as the first responders to pulmonary cryptococcosis; however, their dynamic molecular responses to Cryptococcus gattii infection in vivo remain limited. Here, we investigated the transcriptional profiles of lung alveolar macrophages purified from mice intranasally...

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Huvudupphov: Siranart Jeerawattanawart, Adithap Hansakon, Rudi Alberts, Yongliang Zhang, Pornpimon Angkasekwinai
Materialtyp: Artigo
Språk:Inglês
Utgiven: Public Library of Science (PLoS) 2025-01-01
Serie:PLoS ONE
Länkar:https://doi.org/10.1371/journal.pone.0333090
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