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Production of Mevalonate from Glycerol by <i>Escherichia coli</i> Citrate Synthase Variants

Mevalonate is a biochemical precursor to a wide range of isoprenoids. Because the mevalonate pathway uses three moles of acetyl–CoA, native pathways which metabolize acetyl–CoA, including citrate synthase, strongly compete with mevalonate synthesis. Our hypothesis is that modifications in citrate sy...

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Bibliographic Details
Main Authors: Caroline E. Hartner, Mark A. Eiteman
Format: Artigo
Language:Inglês
Published: MDPI AG 2026-04-01
Series:Fermentation
Subjects:
Online Access:https://www.mdpi.com/2311-5637/12/4/186
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