Prognostic association of immunoproteasome expression in solid tumours is governed by the immediate immune environment

Induction of immunoproteasome (IP) expression in tumour cells can enhance antigen presentation and immunogenicity. Recently, the overexpression of IP genes has been associated with better prognosis and response to immune checkpoint blockade (ICB) therapies in melanoma. However, the extent of this as...

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Autors principals:	Rahul Kumar, Bhavya Dhaka, Sarthak Sahoo, Mohit Kumar Jolly, Radhakrishnan Sabarinathan
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2023-06-01
Col·lecció:	Molecular Oncology
Matèries:	cytotoxic activity immune cell infiltration immune checkpoint blockade immunoproteasome inflammatory response
Accés en línia:	https://doi.org/10.1002/1878-0261.13443
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