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Characterization of early markers of disease in the mouse model of mucopolysaccharidosis IIIB

Abstract Background Mucopolysaccharidosis (MPS) IIIB, also known as Sanfilippo Syndrome B, is a devastating childhood disease. Unfortunately, there are currently no available treatments for MPS IIIB patients. Yet, animal models of lysosomal storage diseases have been valuable tools in identifying pr...

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Principais autores: Katherine B. McCullough, Amanda Titus, Kate Reardon, Sara Conyers, Joseph D. Dougherty, Xia Ge, Joel R. Garbow, Patricia Dickson, Carla M. Yuede, Susan E. Maloney
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-04-01
coleção:Journal of Neurodevelopmental Disorders
Assuntos:
Sanfilippo B
Mucopolysaccharidosis IIIB
Lysosomal storage disorder
Ultrasonic vocalization
Gait
Fear conditioning
Acesso em linha:https://doi.org/10.1186/s11689-024-09534-z
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