Development of the Composition and Technology for Production a Solid Dispersion System by Hot Melt Extrusion to Increase the Bioavailability of the Active Substance

Introduction. The solubility of an active pharmaceutical ingredient plays a major role in drug absorption. Hot melt extrusion is a batch or continuous process that allows creating solid dispersion systems based on various carriers in order to increase solubility and bioavailability of active substan...

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Detalhes bibliográficos

Principais autores:	K. A. Gusev, D. N. Maimistov, V. I. Pavlovsky, A. R. Aliev, A. V. Pavlovsky, O. V. Ivanova, D. O. Tsyrenov, E. V. Flisyuk
Formato:	Artigo
Idioma:	Russo
Publicado em:	LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2022-11-01
coleção:	Разработка и регистрация лекарственных средств
Assuntos:	analgesic 1,4-benzodiazepine hot melt extrusion extrudate solid dispersion solubility bioavailability
Acesso em linha:	https://www.pharmjournal.ru/jour/article/view/1367
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