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Differential regulation of breast cancer-associated genes by progesterone receptor isoforms PRA and PRB in a new bi-inducible breast cancer cell line.

Progesterone receptor isoforms (PRA and PRB) are expressed at equal levels in normal mammary cells. However, alteration in PRA/PRB expression is often observed in aggressive breast cancer suggesting differential contribution of PR isoforms in carcinogenesis. The mechanisms underlying such processes...

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Bibliografiske detaljer
Principais autores: Junaid A Khan, Catherine Bellance, Anne Guiochon-Mantel, Marc Lombès, Hugues Loosfelt
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3454371?pdf=render
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