Glutamate-induced nuclear translocation of PYK2 in hippocampal neurons, interaction with MBD2, and role in cell death in a model of epilepsy

Abstract Synaptic activity results in long-lasting alterations of neuronal properties, which require gene expression regulation. PYK2 is a calcium-activated non-receptor protein tyrosine kinase highly expressed in hippocampal neurons and involved in synaptic functions. PYK2 also shuttles between the...

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Váldodahkkit:	Albert Giralt, Tiago Mendes, Enrica Montalban, Carmen Cifuentes-Diaz, Marcos Galán-Ganga, Margot Chouchana, Benoît de Pins, Sophie Longueville, Damien Carrel, Jean-Antoine Girault
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Nature Publishing Group 2026-04-01
Ráidu:	Cell Death and Disease
Liŋkkat:	https://doi.org/10.1038/s41419-026-08628-x
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