Higher Responsiveness to Rosuvastatin in Polygenic versus Monogenic Hypercholesterolemia: A Propensity Score Analysis

Background: The monogenic defect in familial hypercholesterolemia (FH) is detected in ∼40% of cases. The majority of mutation-negative patients have a polygenic cause of high LDL-cholesterol (LDL-C). We sought to investigate whether the underlying monogenic or polygenic defect is associated with the...

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Autors principals:	Agnieszka Mickiewicz, Marta Futema, Agnieszka Ćwiklinska, Agnieszka Kuchta, Maciej Jankowski, Mariusz Kaszubowski, Magdalena Chmara, Bartosz Wasąg, Marcin Fijałkowski, Miłosz Jaguszewski, Steve E. Humphries, Marcin Gruchała
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2020-05-01
Col·lecció:	Life
Matèries:	polygenic hypercholesterolemia monogenic hypercholesterolemia rosuvastatin propensity score
Accés en línia:	https://www.mdpi.com/2075-1729/10/5/73
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