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Myocardium-Specific Deletion of Rac1 Causes Ventricular Noncompaction and Outflow Tract Defects

Background: Left ventricular noncompaction (LVNC) is a cardiomyopathy that can lead to arrhythmias, embolic events and heart failure. Despite our current knowledge of cardiac development, the mechanisms underlying noncompaction of the ventricular myocardium are still poorly understood. The small GTP...

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Autors principals: Carmen Leung, Anish Engineer, Mella Y. Kim, Xiangru Lu, Qingping Feng
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2021-03-01
Col·lecció:Journal of Cardiovascular Development and Disease
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Accés en línia:https://www.mdpi.com/2308-3425/8/3/29
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