Cutaneous Toll-like Receptor 9 Pre-Defines Hydroxychloroquine Dosage in Patients with Both Discoid and Subacute Lupus Erythematosus

<i>Background and Objectives</i>: Cutaneous lupus erythematosus (CLE) presents clinically heterogeneous manifestations, partially explained by the different expression of Toll-like receptors (TLRs) type 8 and 9, located to endosomal compartments where they are poised to recognize microbial nucleic a...

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Hauptverfasser:	Karolina A. Englert, Grzegorz Dyduch, Agata Kłosowicz, Magdalena Spałkowska, Andrzej Kazimierz Jaworek, Kamila Migacz-Gruszka, Aleksandra Jarosz-Chudek, Santo Raffaele Mercuri, Joanna Szpor, Gianluigi Mazzoccoli, Giovanni Damiani, Anna Wojas-Pelc
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-11-01
Schriftenreihe:	Medicina
Schlagworte:	cutaneous lupus erythematosus discoid lupus erythematosus (DLE) subacute cutaneous lupus erythematosus (SCLE) CLASI hydroxychloroquine response precision medicine
Online-Zugang:	https://www.mdpi.com/1648-9144/59/11/2022
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