Identification and validation of the mode of action of the chalcone anti-mycobacterial compounds

Objectives: The search for new TB drugs has become one of the great challenges for modern medicinal chemistry. An improvement in the outcomes of TB chemotherapy can be achieved by the development of new, shorter, cheap, safe and effective anti-TB regimens. Methods: Chalcones (1a-1o) were synthesized...

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Hlavní autoři:	B. Anagani, J. Singh, J.P. Bassin, G.S. Besra, C. Benham, T.R.K. Reddy, J.A.G. Cox, M. Goyal
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2020-12-01
Edice:	The Cell Surface
Témata:	Chalcones Tuberculosis MIC InhA Mycolic Acids Docking
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2468233020300086
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