Synthesis, In Vitro α-Glucosidase Inhibitory Activity and Molecular Docking Study of New Benzotriazole-Based Bis-Schiff Base Derivatives

This study was carried out to synthesize benzotriazole-based bis-Schiff base scaffolds (<b>1</b>–<b>20</b>) and assess them in vitro for <i>α</i>-glucosidase inhibitory potentials. All the synthetics analogs based on benzotriazole-based bis-Schiff base scaffolds were found to display an outstanding...

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Autors principals:	Imran Khan, Wajid Rehman, Fazal Rahim, Rafaqat Hussain, Shoaib Khan, Srosh Fazil, Liaqat Rasheed, Muhammad Taha, Syed Adnan Ali Shah, Magda H. Abdellattif, Thoraya A. Farghaly
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-12-01
Col·lecció:	Pharmaceuticals
Matèries:	synthesis α-glucosidase benzotriazole bis-Schiff base structure activity relationship molecular docking
Accés en línia:	https://www.mdpi.com/1424-8247/16/1/17
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