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The apelinergic system as an alternative to catecholamines in low-output septic shock

Abstract Catecholamines, in concert with fluid resuscitation, have long been recommended in the management of septic shock. However, not all patients respond positively and controversy surrounding the efficacy-to-safety profile of catecholamines has emerged, trending toward decatecholaminization. Co...

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Principais autores: David Coquerel, Xavier Sainsily, Lauralyne Dumont, Philippe Sarret, Éric Marsault, Mannix Auger-Messier, Olivier Lesur
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-01-01
Serier:Critical Care
Fag:
Apelinergic system
Apelin (APJ) receptor
Biased signaling
Decatecholaminization
Inodilator
Septic shock
Online adgang:http://link.springer.com/article/10.1186/s13054-018-1942-z
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