Anti‐tumor effects of a nonsteroidal anti‐inflammatory drug zaltoprofen on chondrosarcoma via activating peroxisome proliferator‐activated receptor gamma and suppressing matrix metalloproteinase‐2 expression

Abstract Surgical resection is the only treatment for chondrosarcomas, because of their resistance to chemotherapy and radiotherapy; therefore, additional strategies are crucial to treat chondrosarcomas. Peroxisome proliferator‐activated receptor gamma (PPARγ) is a ligand‐activated transcription fac...

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Bibliografische Detailangaben

Hauptverfasser:	Takashi Higuchi, Akihiko Takeuchi, Seiichi Munesue, Norio Yamamoto, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Hiroyuki Inatani, Shingo Shimozaki, Takashi Kato, Yu Aoki, Kensaku Abe, Yuta Taniguchi, Hisaki Aiba, Hideki Murakami, Ai Harashima, Yasuhiko Yamamoto, Hiroyuki Tsuchiya
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2018-05-01
Schriftenreihe:	Cancer Medicine
Schlagworte:	Chondrosarcoma MMP2 nonsteroidal anti‐inflammatory drugs PPAR γ zaltoprofen
Online-Zugang:	https://doi.org/10.1002/cam4.1438
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