The hepatitis E virus capsid protein ORF2 counteracts cell-intrinsic antiviral responses to enable persistent replication in cell culture.

Hepatitis E virus (HEV) is a significant human pathogen causing both acute and chronic infections worldwide. The cell-intrinsic antiviral response serves as the initial defense against viruses and has been shown to be activated upon HEV infection. HEV can replicate in the presence of this response,...

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主要な著者:	Ann-Kathrin Mehnert, Sebastian Stegmaier, Carlos Ramirez Alvarez, Elif Toprak, Vladimir Gonçalves Magalhães, Carla Siebenkotten, Jungen Hu, Ana Luisa Costa, Daniel Kirrmaier, Michael Knop, Xianfang Wu, Thibault Tubiana, Carl Herrmann, Marco Binder, Viet Loan Dao Thi
フォーマット:	Artigo
言語:	Inglês
出版事項:	Public Library of Science (PLoS) 2025-09-01
シリーズ:	PLoS Pathogens
オンライン･アクセス:	https://doi.org/10.1371/journal.ppat.1013516
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