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Assessment of BoHV-4-based vector vaccine intranasally administered in a hamster challenge model of lung disease

IntroductionBovine herpesvirus 4 (BoHV-4) is a bovine Rhadinovirus not associated with a specific pathological lesion or disease and experimentally employed as a viral vector vaccine. BoHV-4-based vector (BoHV-4-BV) has been shown to be effective in immunizing and protecting several animal species w...

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Principais autores: Seok-Chan Park, Laura Conti, Valentina Franceschi, Byungkwan Oh, Myeon-Sik Yang, Gaeul Ham, Antonino Di Lorenzo, Elisabetta Bolli, Federica Cavallo, Bumseok Kim, Gaetano Donofrio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-07-01
coleção:Frontiers in Immunology
Assuntos:
vaccine
lung disease
BoHV-4-based vector
intranasal vaccination
immune response
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1197649/full
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