Generation, characterization, and validation of two human induced pluripotent stem cell lines from the peripheral blood of young and older adults

Aging is a leading risk factor for the development of age-related diseases. However, how aging impacts human induced pluripotent stem cell (hiPSC) reprogramming, age-related epigenetic memory post-reprogramming, differentiation, and its potential applicability to cardiovascular regenerative medicine...

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Detalhes bibliográficos

Principais autores:	Dongli Yang, Jun Chen, Jerry H. Juratli, Andre Monteiro da Rocha, Allison Schley, Nadia R. Sutton
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-03-01
coleção:	Stem Cell Research
Assuntos:	Aging Stem cell Epigenetic Human induced pluripotent stem cell
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1873506125000200
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