Pharmacologic targeting of the P-TEFb complex as a therapeutic strategy for chronic myeloid leukemia
Abstract Background The positive transcription elongation factor b (P-TEFb) kinase activity is involved in the process of transcription. Cyclin-dependent kinase 9 (CDK9), a core component of P-TEFb, regulates the process of transcription elongation, which is associated with differentiation and apopt...
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| Główni autorzy: | , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2021-08-01
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| Seria: | Cell Communication and Signaling |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s12964-021-00764-5 |
| Etykiety: |
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