Hepatic Tumor Cell Morphology Plasticity under Physical Constraints in 3D Cultures Driven by YAP–mTOR Axis

Recent studies undoubtedly show that the mammalian target of rapamycin (mTOR) and the Hippo–Yes-associated protein 1 (YAP) pathways are important mediators of mechanical cues. The crosstalk between these pathways as well as de-regulation of their signaling has been implicated in multiple tumor types...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Adam Frtús, Barbora Smolková, Mariia Uzhytchak, Mariia Lunova, Milan Jirsa, Martin Hof, Piotr Jurkiewicz, Vladimir I. Lozinsky, Lucie Wolfová, Yuriy Petrenko, Šárka Kubinová, Alexandr Dejneka, Oleg Lunov
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2020-11-01
Serier:	Pharmaceuticals
Fag:	mechanotransduction YAP mTOR autophagy 3D cultures cytoskeleton
Online adgang:	https://www.mdpi.com/1424-8247/13/12/430
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!