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Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7.

Legionella pneumophila strains harboring wild-type rpsL such as Lp02rpsLWT cannot replicate in mouse bone marrow-derived macrophages (BMDMs) due to induction of extensive lysosome damage and apoptosis. The bacterial factor directly responsible for inducing such cell death and the host factor involve...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Chuang Li, Jiaqi Fu, Shuai Shao, Zhao-Qing Luo
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2024-05-01
Rangatū:PLoS Pathogens
Urunga tuihono:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011783&type=printable
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