Cancer immunotherapy by adenosinergic CD39 and CD73 as emerging immune checkpoints
Abstract Extracellular adenosine has recently been identified as an immunological checkpoint mediator that hinders the immune response to malignancies. The production of adenosine is facilitated by the enzymatic activity of CD39 and CD73. There is an increasing body of evidence suggesting that CD39...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer
2025-11-01
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| Series: | Discover Oncology |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1007/s12672-025-04001-0 |
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