Proteolytic Activation of the Epithelial Sodium Channel in Nephrotic Syndrome by Proteasuria: Concept and Therapeutic Potential
The epithelial sodium channel (ENaC) is expressed in the aldosterone-sensitive distal nephron, and it determines the final urinary sodium concentration. To ensure sodium preservation, ENaC-mediated sodium transport is redundantly regulated by several mechanisms. Among them, activation by proteases i...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Turkish Society of Nephrology
2020-02-01
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| Col·lecció: | Turkish Journal of Nephrology |
| Matèries: | |
| Accés en línia: | https://turkjnephrol.org/index.php/pub/article/view/1331 |
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