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α‐Adrenergic blockade impairs ductus venosus shunting during an acute period of fetal hypoxaemia without further deficits to cerebral oxygen delivery

Abstract The fetal circulation has unique shunts, including the ductus venosus (DV), the tone of which dictates how much substrate‐rich blood returning from the placenta is streamed preferentially away from the liver and instead towards the heart. Herein, we aimed to use clinically relevant MRI tech...

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Principais autores: Jack R. T. Darby, Stacey L. Holman, Brahmdeep S. Saini, Sunthara Rajan Perumal, Mike Seed, Christopher K. Macgowan, Janna L. Morrison
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2026-04-01
Serier:Experimental Physiology
Fag:
α‐adrenergic
ductus venosus
fetus
hypoxaemia
hypoxia
magnetic resonance imaging
Online adgang:https://doi.org/10.1113/EP093085
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