Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease

Dyskinesia seen in the off-state, referred as graft-induced dyskinesia (GID), has emerged as a serious complication induced by dopamine (DA) cell transplantation in parkinsonian patients. Although the mechanism underlying the appearance of GID is unknown, in a recent clinical study the partial 5-HT1...

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Detalhes bibliográficos

Principais autores:	Eunju Shin, Joanna Garcia, Christian Winkler, Anders Björklund, Manolo Carta
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2012-09-01
coleção:	Neurobiology of Disease
Assuntos:	Graft-induced dyskinesia L-DOPA-induced dyskinesia Parkinson's disease Serotonin Dopamine D2 receptor Cell transplantation
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996112001271
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