Determination of βS haplotypes in patients with sickle-cell anemia in the state of Rio Grande do Norte, Brazil

βS haplotypes were studied in 47 non-related patients with sickle-cell anemia from the state of Rio Grande do Norte, Brazil. Molecular analysis was conducted by PCR/RFLP using restriction endonucleases XmnI, HindIII, HincII and HinfI to analyze six polymorphic sites from the beta cluster. Twent...

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Autors principals:	Cynthia Hatsue Kitayama Cabral, Édvis Santos Soares Serafim, Waleska Rayane Dantas Bezerra de Medeiros, Thales Allyrio Araújo de Medeiros Fernandes, Elza Miyuki Kimura, Fernando Ferreira Costa, Maria de Fátima Sonati, Ivanise Marina Moretti Rebecchi, Tereza Maria Dantas de Medeiros
Format:	Artigo
Idioma:	Inglês
Publicat:	Sociedade Brasileira de Genética 2011-01-01
Col·lecció:	Genetics and Molecular Biology
Matèries:	haplotypes β-globin sickle-cell anemia Brazilian population S hemoglobin
Accés en línia:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000300009
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