BRISC inactivation alleviates alcohol-induced liver injury in mice

Abstract BRCC3 isopeptidase complex (BRISC) is a JAMM subfamily deubiquitinase that has been revealed to be required for optional activation of NLRP3 inflammasome and TLR4/NF-κB signaling pathway. BRISC plays an important role in lipopolysaccharide (LPS)/D-galactosamine-induced acute liver failure,...

Descrición completa

Detalles Bibliográficos

Principais autores:	Ting Wang, Wen Zhang, Xian Liu, Kai Liu, Guang-Ming Ren, Shen-Si Xiang, Yi-Qun Zhan, Hui Chen, Hui-Ying Gao, Ke Zhao, Miao Yu, Chang-Yan Li, Xiao-Ming Yang, Rong-Hua Yin
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2025-02-01
Series:	Scientific Reports
Assuntos:	Alcoholic liver disease BRISC Thiolutin Liver steatosis Inflammation NLRP3 inflammasome
Acceso en liña:	https://doi.org/10.1038/s41598-025-89796-2
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!