Steric‐Adaptive Biocatalysis: Imine Reductase‐Mediated Dynamic Kinetic Resolution for Atroposelective Synthesis of Hindered Biaryl Amines
Abstract As an efficient and environmentally benign strategy, enzymatic catalysis has emerged with high reactivity and selectivity for atropisomeric structures. Atropisomeric biaryl amines are of great importance in drug development and asymmetric catalysis. However, substrates with steric hindrance...
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| Principais autores: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley
2025-12-01
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| Serier: | Advanced Science |
| Fag: | |
| Online adgang: | https://doi.org/10.1002/advs.202510455 |
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