DIAPH1 regulates chromosomal instability of cancer cells by controlling microtubule dynamics
Chromosomal instability (CIN) is a hallmark of cancer, resulting from misalignment and missegregation of chromosomes during meta- and anaphase, due to non-precise regulation of spindle-MT dynamics. Diaphanous Related Formin 1 (DIAPH1) is an actin nucleator and also binds microtubule (MT) with high a...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021-04-01
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| coleção: | European Journal of Cell Biology |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S0171933521000078 |
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