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MLKL is involved in the regulation of skin wound healing and interplay between macrophages and myofibroblasts in mice

Abstract Mixed lineage kinase domain-like protein (MLKL), a critical necroptosis effector, is strongly linked to inflammation, a key component of skin wound healing. However, its precise role in the wound healing process remains inadequately characterized. This study revealed sustained MLKL overexpr...

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Principais autores: Jiamin Zhao, Shuangyi Zhang, Yunjie Bai, Zhiguo Gong, Wenhui Bao, Zhuoya Yu, Bo Liu, Wei Mao, Surong Hasi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-04-01
Serier:Scientific Reports
Fag:
Skin
Wound healing
MLKL
Macrophages
Myofibroblasts
Online adgang:https://doi.org/10.1038/s41598-025-97729-2
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