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Decoding atherosclerosis through lactylation: multi-omics integration with experimental validation

BackgroundAtherosclerosis (AS) remains a major cause of cardiovascular morbidity and mortality. Lactylation—a recently described post-translational modification linking cellular metabolism to gene regulation—has been implicated in vascular inflammation, yet its roles in AS are not fully defined.Meth...

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Hauptverfasser: Yirong Ma, Qiming Li, Muge Wang, Qiang Wan, Junyu Lai, Jianguang Wu, Shuguang Wu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-05-01
Schriftenreihe:Frontiers in Cell and Developmental Biology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fcell.2026.1742425/full
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