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Prenatal selective serotonin reuptake inhibitor (SSRI) exposure induces working memory and social recognition deficits by disrupting inhibitory synaptic networks in male mice

Abstract Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed antidepressant drugs in pregnant women. Infants born following prenatal exposure to SSRIs have a higher risk for behavioral abnormalities, however, the underlying mechanisms remains unknown. Therefore, we examined the e...

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Principais autores: Weonjin Yu, Yi-Chun Yen, Young-Hwan Lee, Shawn Tan, Yixin Xiao, Hidayat Lokman, Audrey Khoo Tze Ting, Hasini Ganegala, Taejoon Kwon, Won-Kyung Ho, H. Shawn Je
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-04-01
Serier:Molecular Brain
Fag:
Prenatal
Serotonin (5-HT)
Selective serotonin reuptake inhibitor (SSRI)
Fluoxetine
Working memory
Social recognition
Online adgang:http://link.springer.com/article/10.1186/s13041-019-0452-5
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