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Validation of Recombinant Heparan Sulphate Reagents for CNS Repair

Therapies that target the multicellular pathology of central nervous system (CNS) disease/injury are urgently required. Modified non-anticoagulant heparins mimic the heparan sulphate (HS) glycan family and have been proposed as therapeutics for CNS repair since they are effective regulators of numer...

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Autori principali: Susan L. Lindsay, Rebecca Sherrard Smith, Edwin A. Yates, Colin Cartwright, Bryan E. Thacker, Jeremy E. Turnbull, Charles A. Glass, Susan C. Barnett
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2023-03-01
Serie:Biology
Soggetti:
heparan sulphate
recombinant heparin mimetics
CNS repair
remyelination
neurite outgrowth
Accesso online:https://www.mdpi.com/2079-7737/12/3/407
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