S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability in multiple myeloma

Multiple myeloma (MM) is the second most prevalent hematologic malignancy and is incurable because of the inevitable development of drug resistance. Methionine adenosyltransferase 2α (MAT2A) is the primary producer of the methyl donor S-adenosylmethionine (SAM) and several studies have documented M...

詳細記述

書誌詳細

主要な著者:	Yanmeng Wang, Catharina Muylaert, Arne Wyns, Philip Vlummens, Kim De Veirman, Karin Vanderkerken, Esther Zaal, Celia Berkers, Jérome Moreaux, Elke De Bruyne, Eline Menu
フォーマット:	Artigo
言語:	Inglês
出版事項:	Ferrata Storti Foundation 2023-07-01
シリーズ:	Haematologica
オンライン･アクセス:	https://haematologica.org/article/view/11167
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