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Macrophage-Specific NLRC5 Protects From Cardiac Remodeling Through Interaction With HSPA8

Summary: Macrophages regulate inflammation and the process of tissue repair. Therefore, a better understanding of macrophages in the pathogenesis of heart failure is needed. In patients with hypertrophic cardiomyopathy, NLRC5 was significantly increased in circulating monocytes and cardiac macrophag...

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Asıl Yazarlar: Qing Yu, MD, Peinan Ju, PhD, Wenxin Kou, PhD, Ming Zhai, PhD, Yanxi Zeng, MD, Nuerbiyemu Maimaitiaili, MD, Yefei Shi, PhD, Xu Xu, PhD, Yifan Zhao, PhD, Weixia Jian, PhD, Mark W. Feinberg, PhD, Yawei Xu, PhD, Jianhui Zhuang, PhD, Wenhui Peng, PhD
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2023-05-01
Seri Bilgileri:JACC: Basic to Translational Science
Konular:
cardiac remodeling
heart failure
immunomodulatory therapy
macrophages
NOD-like receptor
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2452302X22003722
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