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Generation of a homozygous DNAJC19 knockout human embryonic stem cell line by CRISPR/Cas9 system

The DNAJC19 gene, a member of DNAJ heat shock protein (Hsp40) family, is localized within the inner mitochondrial membrane (IMM) and plays a crucial role in regulating the function and localization of mitochondrial Hsp70 (MtHsp70). Mutations in the DNAJC19 gene cause Dilated Cardiomyopathy with Atax...

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Auteurs principaux: Guangduo Chen, Rui Bai, Pufeng Huang, Xujie Liu, Jie Ni, Lianglong Chen
Format: Artigo
Langue:Inglês
Publié: Elsevier 2024-06-01
Collection:Stem Cell Research
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S1873506124001259
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