Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates

A series of monothiocarbamates (MTCs) was investigated for the inhibition of the β-class carbonic anhydrase (CAs, EC 4.2.1.1) from the fungal parasite Malassezia globosa, MgCA. These MTCs incorporate various scaffolds, among which aliphatic amine with 1–4 carbons atom in their molecule, morpholine,...

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Detalhes bibliográficos

Principais autores:	Alessio Nocentini, Daniela Vullo, Sonia Del Prete, Sameh M. Osman, Fatmah A.S. Alasmary, Zeid AlOthman, Clemente Capasso, Fabrizio Carta, Paola Gratteri, Claudiu T. Supuran
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2017-01-01
coleção:	Journal of Enzyme Inhibition and Medicinal Chemistry
Assuntos:	Carbonic anhydrase β-CA-class enzyme monothiocarbamate inhibitor Malassezia globosa
Acesso em linha:	http://dx.doi.org/10.1080/14756366.2017.1355307
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