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Rotary mechanism of V/A-ATPases—how is ATP hydrolysis converted into a mechanical step rotation in rotary ATPases?

V/A-ATPase is a rotary molecular motor protein that produces ATP through the rotation of its central rotor. The soluble part of this protein, the V1 domain, rotates upon ATP hydrolysis. However, the mechanism by which ATP hydrolysis in the V1 domain couples with the mechanical rotation of the rotor...

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Autor principal: Ken Yokoyama
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2023-04-01
Col·lecció:Frontiers in Molecular Biosciences
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1176114/full
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