Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor
Abstract The neuropeptide 26RFa, a member of the RF-amide peptide family, activates the pyroglutamylated RF-amide peptide receptor (QRFPR), a class A GPCR. The 26RFa/QRFPR system plays critical roles in energy homeostasis, making QRFPR an attractive drug target for treating obesity, diabetes, and ea...
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2024-06-01
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| Seri Bilgileri: | Cell Discovery |
| Online Erişim: | https://doi.org/10.1038/s41421-024-00670-3 |
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