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Antioxidant Defense by Thioredoxin Can Occur Independently of Canonical Thiol-Disulfide Oxidoreductase Enzymatic Activity

The thiol-disulfide oxidoreductase CXXC catalytic domain of thioredoxin contributes to antioxidant defense in phylogenetically diverse organisms. We find that although the oxidoreductase activity of thioredoxin-1 protects Salmonella enterica serovar Typhimurium from hydrogen peroxide in vitro, it do...

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Váldodahkkit: Miryoung Song, Ju-Sim Kim, Lin Liu, Maroof Husain, Andrés Vázquez-Torres
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2016-03-01
Ráidu:Cell Reports
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2211124716301887
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