Comparison of the pharmacokinetics and pharmacodynamics of apixaban and rivaroxaban in dogs

Abstract Background Comparative pharmacokinetics and pharmacodynamics (PK/PD) of apixaban and rivaroxaban have not been studied in dogs and the propensity of these drugs to cause hypercoagulability after discontinuation is unknown. Hypothesis Compare the PK/PD of clinical dosing regimens of PO apixa...

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Principais autores:	Alex M. Lynch, Laura K. Ruterbories, Yao Zhu, Frank Fialkiewicz, Mark G. Papich, Marjory B. Brooks, Robert Goggs
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 2024-11-01
Serija:	Journal of Veterinary Internal Medicine
Teme:	anticoagulant anti‐Xa direct oral anticoagulant DOAC thrombin generation thromboprophylaxis
Online dostop:	https://doi.org/10.1111/jvim.17216
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