Body mass index adjusted aspirin dosing does not overcome pharmacokinetic and pharmacodynamic disadvantages in obese pregnant women at risk for preeclampsia: a prospective cohort study

ObjectiveTo assess if aspirin dosed based on a patient's body mass index (BMI) would yield similar pharmacokinetics and pharmacodynamics for obese compared to non-obese patients who are taking aspirin to prevent preeclampsia.MethodsThis prospective cohort study included 35 pregnant women at high-ris...

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Autors principals:	Fulya Sultan Karaduman, Numan Cim, Meltem Caliskan, Bünyamin Cim, Seval Yilmaz Ergani, Filiz Yarsilikal Guleroglu, Ali Cetin
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-05-01
Col·lecció:	Frontiers in Medicine
Matèries:	aspirin resistance obesity pharmacokinetics preeclampsia pregnancy thromboxane B2
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1810134/full
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